High Wycombe · Buckinghamshire
Polynucleotides in High Wycombe
Polynucleotides are injectable treatments used to support skin quality, hydration and elasticity, including the delicate under-eye area. The product is chosen for your skin at consultation, because different preparations suit different concerns.

Skin quality, not volume
Polynucleotides focus on the condition of the skin rather than adding shape. They are commonly discussed for thin, crepey or tired-looking skin.
Chosen at consultation
Marci assesses your skin and recommends the approach and number of sessions. Treatment is from £120.
Realistic expectations
Changes are gradual and vary between people. Treatment is not a promise to remove dark circles or lines.
Key benefits
- Supports skin quality, hydration and elasticity.
- Commonly used for the delicate under-eye area and crepey skin.
- Does not add volume or change facial shape.
- Product selected for your skin at consultation.
Who it may suit
- Adults with thin, crepey or tired-looking skin, including under the eyes.
- Not suitable for people with a fish or salmon allergy, as products are derived from fish DNA.
What happens during treatment
- Consultation and skin assessment.
- Skin is cleansed; numbing cream may be used.
- Small amounts are injected with a fine needle or cannula.
Results and recovery
- Small bumps, redness or swelling usually settle within a few days.
- Bruising may occur, particularly under the eyes.
- Gradual improvement over a course of sessions; results vary.
Aftercare essentials
- Avoid touching or massaging the area unless advised.
- Avoid make-up on treated skin for around 12–24 hours.
- Avoid heat (saunas, steam, hot yoga), strenuous exercise and alcohol for 24–48 hours.
- Contact the clinic straight away about increasing pain, skin colour changes, blanching or vision changes.
Contraindications and precautions
- Pregnancy or breastfeeding — treatment is usually postponed.
- Active skin infection, cold sores, open wounds or inflamed skin in the area.
- Tell us about medical conditions, medicines (including blood thinners), allergies and recent treatments.
- Autoimmune conditions, bleeding disorders or a history of keloid scarring need careful assessment.
- Recent dental work, vaccinations or illness may mean waiting before treatment.
- Fish or salmon allergy.
Consultation and booking
Every treatment begins with a consultation and suitability assessment, and your practitioner will advise on the plan, sessions and recovery for you. A deposit is taken when booking online. Injectable and prescription treatments need at least 48 hours' notice.
Skin Boosters & Regenerative prices
- Polynucleotidesfrom £120
- Polynucleotides, 3 sessionsfrom £285
- Polynucleotides, 6 sessionsfrom £575
Eligible 3- and 6-session skin courses save at least 20%, rounded down to £5, with no joining fee. Scalp courses and the two-session Profhilo offer have separate fixed prices. Session numbers, spacing and quantities are agreed after assessment; courses are not a recommendation for extra treatment.
Questions
- How much do polynucleotides cost?
- From £120. Your final plan and price are confirmed at consultation.
- When should I book?
- Polynucleotides are an injectable treatment, so please book at least 48 hours ahead.
Visit our High Wycombe clinic
The Old Library, Patch Places, Queen Victoria Road, High Wycombe, HP11 1BG. Within easy reach of Hazlemere, Beaconsfield, Marlow, Amersham, Princes Risborough, Great Missenden and the wider Buckinghamshire area.
Every treatment follows a consultation and suitability assessment. Individual results vary.
